Our pediatric facility is updating our clinical standard on treatment of infiltrates and extravasations in the pediatric patient. I would appreciate any feedback on the following questions including references and evidence to guide this practice. 1. What age groups do you utilize cold packs in treatment? 2. Is the cold pack applied pre or post hyaluronidase treatment? 3. What length of time do you recommend to apply the cold pack for effectiveness? Any information will be greatly appreciated.