Meds pH & osmol

Previously IVaccess.com, quick reference list of irritant & vesicant medications for professionals working in IV therapy or related areas. Note: all data from pharmaceutical references. Osmolarities vary depending on local pharmacy mix.

IV MedicationpH typical osm/L
 A
acyclovir (zovirax)10.5 - 11.6316
aldesleukin7.8
amikacin3.5 - 5.5349
aminocaproic acid6.0 - 7.6
aminophylline8.6 - 9327
amiodarone4.1
amobarbital9.6 - 10.4
amphotericin b5.0 - 6.0
ampicillin sodiumsee info
azlocillin6.0 - 8.0
aztreonam4.5 - 7.5
 B
bleomycin4.0 - 6.0
bortezomib2.0 - 6.5
bumetanide6.8 - 7.8
 C
calcium chloride5.5 - 7.5
calcium gluconate6-8.2
carboplatin5.0 - 7.0
carmustine5.6 - 6.0
cefamandole6.0 - 8.5
cefazolin4.5 - 6.0
cefepime4.0 - 6.0
cefotetan4.5 - 6.5
cefoxitin4.2 - 7.0
ceftazidime5.0 - 8.0
ceftriaxone6.7
cefuroxime6.0 - 8.5
cephapirin6.8 - 8.5
ciprofloxacine3.3 - 4.6
cisplatin3.8 - 5.9
clofarabine6.0-8.0
cyclophosphamidesee info
 D
dacarbazine3.0 - 4.0
dactinomycin5.5 - 7.0
dalbavancin (Dalvance)4.5246
daunorubicin4.5
deferoxamine4.9
dextrose 10% or greater3.5-6.5500-2526
diazepam6.27000
diltiazemsee info
dobutamine2.5 - 5.5
dolasetron3.2 - 3.8
dopamine2.5
doxapram3.5
doxorubicin3.8
doxycycline, vibramycin1.8 - 3.3310
 E
edetate disodium6.5 - 7.5
epinephrine2.5-5
epirubicin3.0
esmolol3.x
etoposide3.0 - 4.0
 F
floxuridine4.0 - 5.5
fluconazolesee info
flumazenil4.0
fluorouracil8.9 - 9.2
fluorouracil, 5fu9.2
foscarnet7.4
 G
ganciclovir sodium9-11
gatifloxacin3.5 - 5.5
gemcitabine2.7 - 3.3
gentamicinsee info
 H
hydromorphone, dilaudid4.0 - 5.5
 I
idarubicin3.5
ifosfamide6.0
imipenem4.5 - 7.0
immune globulin4.0 - 7.2258 - 380
irinotecan3.0 - 3.8
iron dextran5.2 - 6.5
 L
levofloxacinsee info
linezolid4.8
lorazepam, ativan5.7
 M
mannitol4.5 - 7274-1098
mechlorethamine3.0 - 5.0
meperidine3.5 - 6.0
meropenem7.3 - 8.3300
metaraminol3.2 - 4.5
methocarbamol3.5 - 6.0
methotrexate7.5 - 9.0
metoclopramide2.5 - 6.5
metronidazole (flagyl)4.5-7.0310
mezlocillin4.5 - 8.0
midazolam2.9 - 3.7
milrinone3.2 - 4.0
minocycline2.0 - 2.8
mitomycin6.0 - 8.0
mitoxantrone3.0 - 4.5
morphine2.5 - 6.5
moxifloxacin4.1-4.6
 N
nafcillin6.0 - 8.5
netilmicin3.5 - 6.0
nicardipinesee info
nitroprusside3.5 - 6.0
norepinephrine3.0 - 4.5
 O
octreotide3.9 - 4.5
ofloxacin3.5 - 5.5
ondansetron3.0-4.0270
oxacillinsee info
oxaliplatin4.8 - 5.7
 P
paclitaxel4.4 - 5.6
pantoprazole, protonix9.0 - 10.5
pegaspargase7.3
pentamidinesee info
pentobarbital9.0 - 10.5
pentostatin7.0 - 8.5
pentothal10.2 - 11.0
phenytoin12
piperacillin5.5 - 7.5
potassium 20KCL4.0 - 8.0
potassium over 40 kcl4.0 - 8.0
promazine4.0 - 5.5
promethazine, phenergan4.0 - 5.5
propofolsee info
 Q
quinupristin-dalfopristin5.0
 R
rifampin7.8 - 8.8
rocuronium4.0
 S
sodium bicarbonate8.3
streptozocin3.5 - 4.5
 T
teniposide5.0
thiopental10.2 - 11.2
ticarcillin6.0 - 8.0
topotecan2.5 - 3.5
 V
vancomycin2.5 - 4.5
vinblastine3.0 - 5.0
vincristine3.5 - 5.5
vindesine4.2 - 4.5
vinorelbine3.5
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