Previously IVaccess.com, quick reference list of irritant & vesicant medications for professionals working in IV therapy or related areas. Note: all data from pharmaceutical references. Osmolarities vary depending on local pharmacy mix.
| IV Medication | pH | typical osm/L |
| A | | |
|---|
| acyclovir (zovirax) | 10.5 - 11.6 | 316 |
| aldesleukin | 7.8 | |
| amikacin | 3.5 - 5.5 | 349 |
| aminocaproic acid | 6.0 - 7.6 | |
| aminophylline | 8.6 - 9 | 327 |
| amiodarone | 4.1 | |
| amobarbital | 9.6 - 10.4 | |
| amphotericin b | 5.0 - 6.0 | |
| ampicillin sodium | see info | |
| azlocillin | 6.0 - 8.0 | |
| aztreonam | 4.5 - 7.5 | |
| B | | |
|---|
| bleomycin | 4.0 - 6.0 | |
| bortezomib | 2.0 - 6.5 | |
| bumetanide | 6.8 - 7.8 | |
| C | | |
|---|
| calcium chloride | 5.5 - 7.5 | |
| calcium gluconate | 6-8.2 | |
| carboplatin | 5.0 - 7.0 | |
| carmustine | 5.6 - 6.0 | |
| cefamandole | 6.0 - 8.5 | |
| cefazolin | 4.5 - 6.0 | |
| cefepime | 4.0 - 6.0 | |
| cefotetan | 4.5 - 6.5 | |
| cefoxitin | 4.2 - 7.0 | |
| ceftazidime | 5.0 - 8.0 | |
| ceftriaxone | 6.7 | |
| cefuroxime | 6.0 - 8.5 | |
| cephapirin | 6.8 - 8.5 | |
| ciprofloxacine | 3.3 - 4.6 | |
| cisplatin | 3.8 - 5.9 | |
| clofarabine | 6.0-8.0 | |
| cyclophosphamide | see info | |
| D | | |
|---|
| dacarbazine | 3.0 - 4.0 | |
| dactinomycin | 5.5 - 7.0 | |
| dalbavancin (Dalvance) | 4.5 | 246 |
| daunorubicin | 4.5 | |
| deferoxamine | 4.9 | |
| dextrose 10% or greater | 3.5-6.5 | 500-2526 |
| diazepam | 6.2 | 7000 |
| diltiazem | see info | |
| dobutamine | 2.5 - 5.5 | |
| dolasetron | 3.2 - 3.8 | |
| dopamine | 2.5 | |
| doxapram | 3.5 | |
| doxorubicin | 3.8 | |
| doxycycline, vibramycin | 1.8 - 3.3 | 310 |
| E | | |
|---|
| edetate disodium | 6.5 - 7.5 | |
| epinephrine | 2.5-5 | |
| epirubicin | 3.0 | |
| esmolol | 3.x | |
| etoposide | 3.0 - 4.0 | |
| F | | |
|---|
| floxuridine | 4.0 - 5.5 | |
| fluconazole | see info | |
| flumazenil | 4.0 | |
| fluorouracil | 8.9 - 9.2 | |
| fluorouracil, 5fu | 9.2 | |
| foscarnet | 7.4 | |
| G | | |
|---|
| ganciclovir sodium | 9-11 | |
| gatifloxacin | 3.5 - 5.5 | |
| gemcitabine | 2.7 - 3.3 | |
| gentamicin | see info | |
| H | | |
|---|
| hydromorphone, dilaudid | 4.0 - 5.5 | |
| I | | |
|---|
| idarubicin | 3.5 | |
| ifosfamide | 6.0 | |
| imipenem | 4.5 - 7.0 | |
| immune globulin | 4.0 - 7.2 | 258 - 380 |
| irinotecan | 3.0 - 3.8 | |
| iron dextran | 5.2 - 6.5 | |
| L | | |
|---|
| levofloxacin | see info | |
| linezolid | 4.8 | |
| lorazepam, ativan | 5.7 | |
| M | | |
|---|
| mannitol | 4.5 - 7 | 274-1098 |
| mechlorethamine | 3.0 - 5.0 | |
| meperidine | 3.5 - 6.0 | |
| meropenem | 7.3 - 8.3 | 300 |
| metaraminol | 3.2 - 4.5 | |
| methocarbamol | 3.5 - 6.0 | |
| methotrexate | 7.5 - 9.0 | |
| metoclopramide | 2.5 - 6.5 | |
| metronidazole (flagyl) | 4.5-7.0 | 310 |
| mezlocillin | 4.5 - 8.0 | |
| midazolam | 2.9 - 3.7 | |
| milrinone | 3.2 - 4.0 | |
| minocycline | 2.0 - 2.8 | |
| mitomycin | 6.0 - 8.0 | |
| mitoxantrone | 3.0 - 4.5 | |
| morphine | 2.5 - 6.5 | |
| moxifloxacin | 4.1-4.6 | |
| N | | |
|---|
| nafcillin | 6.0 - 8.5 | |
| netilmicin | 3.5 - 6.0 | |
| nicardipine | see info | |
| nitroprusside | 3.5 - 6.0 | |
| norepinephrine | 3.0 - 4.5 | |
| O | | |
|---|
| octreotide | 3.9 - 4.5 | |
| ofloxacin | 3.5 - 5.5 | |
| ondansetron | 3.0-4.0 | 270 |
| oxacillin | see info | |
| oxaliplatin | 4.8 - 5.7 | |
| P | | |
|---|
| paclitaxel | 4.4 - 5.6 | |
| pantoprazole, protonix | 9.0 - 10.5 | |
| pegaspargase | 7.3 | |
| pentamidine | see info | |
| pentobarbital | 9.0 - 10.5 | |
| pentostatin | 7.0 - 8.5 | |
| pentothal | 10.2 - 11.0 | |
| phenytoin | 12 | |
| piperacillin | 5.5 - 7.5 | |
| potassium 20KCL | 4.0 - 8.0 | |
| potassium over 40 kcl | 4.0 - 8.0 | |
| promazine | 4.0 - 5.5 | |
| promethazine, phenergan | 4.0 - 5.5 | |
| propofol | see info | |
| Q | | |
|---|
| quinupristin-dalfopristin | 5.0 | |
| R | | |
|---|
| rifampin | 7.8 - 8.8 | |
| rocuronium | 4.0 | |
| S | | |
|---|
| sodium bicarbonate | 8.3 | |
| streptozocin | 3.5 - 4.5 | |
| T | | |
|---|
| teniposide | 5.0 | |
| thiopental | 10.2 - 11.2 | |
| ticarcillin | 6.0 - 8.0 | |
| topotecan | 2.5 - 3.5 | |
| V | | |
|---|
| vancomycin | 2.5 - 4.5 | |
| vinblastine | 3.0 - 5.0 | |
| vincristine | 3.5 - 5.5 | |
| vindesine | 4.2 - 4.5 | |
| vinorelbine | 3.5 | |
ph-medications-comments-references.pdf