When rounding on our PICC lines today I came across a PICC line without a cap on the end of the red port and blood visible in the lumen. The nurse states that it must have happened 2.5hours ago after the patient recieved blood. The open ended lumen was lying on the sheets in the patient's bed. The patient is on isolation for MRSA and his diagnosis is pneumonia. My question is, should the PICC line come out and be cultured and replaced? And is there an amount of time that can go by when you can keep the PICC, clean the end and withdraw off of it before flushing to keep it?