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Does anyone use Hyaluronidase for contrast media extravasations? Where I am currently employed, the nurses in CT scan haven't even heard of this medication. At a previous hospital, we used to administer Hyaluronidase for CT contrast media extravasations. However, this was approximately 8 years ago. The constrast media my current ogranization uses is Omnipaque, which is administered with a power injector. Any thoughts would be apprectiated.

Thank you,


There are published studies

There are published studies supporting the use of hyaluronidase for contrast extravasation, although the American College of Radiology Manual on Contrast Media does not recommend its use, stating there is a lack of evidence. 

Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI

Lynn Hadaway Associates, Inc.

PO Box 10

Milner, GA 30257


Office Phone 770-358-7861

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