23 yo G1P1 with vonWillebrand's, Â 5 Fr Groshong DL placed on 8/9/07 for Humate P infusionsÂ after infusions of Factor 8Â brought her VWB antigen to around or slightly above 100 and her factor 8 assay to 140 with range 61-192.
Uncomplicated course, pt. delivered baby, PICC line stayed in place with no problems until removal.
9/24 PICC line removed (?because treatment completed?Â noÂ record), had sudden onset of shaking/chills, fever of 101.2F.Â Blood cultures negative, WBC had been normal from insertion time through the episode that caused her to present in the ED.
Comments?Â IncreasedÂ risk of thrombi in these patients with theÂ Factor 8 infusions?Â and then septic thrombi/emboli?
Anyone else have experience with this?Â
MariChief Complaint: FEVER and CHILLS.Onset was abrupt (p PICC LINE REMOVAL).Â Pain level now: 0/10.Â The patient has had fever of 101.2 F orally with chills.