I think there are discussions on this site from previous discussions that you could search.
I don't agree with INR over 2.8 being a point of refusal. We have placed PICCs with INR over 4 without complications. A PICC is definitely safer that a chest placed line with elevated INR, because you can place pressure on the site peripherally.
Please do a search for other comments about this.
The few oozers we have had (some don't start until several days after placement?) we have the staff place several folded 4x4's over dressing (not to change the dressing for 24h), wrap site entirely with Kerlix type wrap and the wrap with light pressure using Ace wrap. This has worked every time. If it did not work, I would then search for another reason such as a nicked superficial artery? or orther causes. We then have them change the dressing the next day. To keep changing the dressing is futile until the site settles down a bit.