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Drawing blood from PICC's and Central Lines

Has anyone come across any research in regard to drawing blood from PICC's and Central Lines?  Does it increase the risk of infection within the catheter?  We've been taught to check for a blood return every shift.  How is this any different?  We have a few physicians who will not allow the nurses to draw blood from their central lines.  I feel if the blood draws are done properly with adequete flushing afterward, how is it increasing the risk of infection?  We have other physicians who write standing orders that it's fine for staff to draw blood from PICC's/Central lines.   

Any insight would be greatly appreciated!

Thank you,

Ann (PICC nurse)

Midland, MI