I have placed more than 150 PICCs. Yesterday, I tried to access a basilic and a brachial vein. Both veins were medium-large lovely black holes on the ultrasound screen. Each vein was 1cm deep and I used a 1cm needle guide. I could see the needle in the middle of the vein. No blood. I tried both veins twice with the same result. The patient was tense and very willing. Venous spasm? Can anyone tell me what was happened?