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Robbin George
Decloting Agents
If a Central Line occlusion is known to be caused by a drug percipitate what is the best safest and most efficient way to resolve the problem--Are there specific antidotes for specific percipitates and if so what refernece source can be used to write policy--I have exchanged PICC in the past to resolve this problem but others want to know if this is Best Practice--Thank you in advance of your responses 
lynncrni
For drugs with a alkaline
For drugs with a alkaline pH, use sodium bicarbonate. For drugs with an acidic pH, use hydrocloric acid. There are many articles about this. Lynn

Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI

Lynn Hadaway Associates, Inc.

PO Box 10

Milner, GA 30257

Website http://www.hadawayassociates.com

Office Phone 770-358-7861

Robbin George
I have searched the internet
I have searched the internet looking for articles with NO result--Firstly are others using such chemical interventions and if so could you post your guidelines policy and procedure for their administration--Seems like a complicated situation for a staff nurse to deal with and one that would require a specific set of competencies 

Robbin George RN VA-BC

lynncrni
Here are a few: 1.   

Here are a few:

1.    Duffy LF, Kerzner B, Gebus V, Dice J. Treatment of central venous catheter occlusions with hydrochloric acid. Journal of Pediatrics. 1989;114(6):1002-1004.
2.    Pennington CR, Pithie AD. Ethanol lock in the management of catheter occlusion. Journal of Parenteral and Enteral Nutrition. 1987;11(5):507-508.
3.    Werlin SL, Lausten T, Jessen S, et al. Treatment of central venous catheter occlusions with ethanol and hydrochloric acid. Journal of Parenteral and Enteral Nutrition. 1994;19(5):416-418.
 

Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI

Lynn Hadaway Associates, Inc.

PO Box 10

Milner, GA 30257

Website http://www.hadawayassociates.com

Office Phone 770-358-7861

Gwen Irwin
You might the ONS Vascular

You might the ONS Vascular Access Guidelines for a table that has what agent to use to declot precipitants.  I don't have the most current version, but have seen in the previous 2 versions.

Gwen Irwin

Austin, Texas

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