I am a member of a committee looking into the use of TKO IVs. I work in the ICU and we have patients that need frequent antibiotics and we use TKO IVs frequently. Unfortunately we do so either without an order or with an order that reads â€œTKO IVâ€. In order to rectify this we are building a TKO IV order set. In order to get this order set through the various committees that are required for approval we need to back this order set with some evidence. So I have two questions I would like feedback on:
1. Reading past discussions on this site I have seen people say that there is no evidence that any specific low rate helps to maintain catheter patency, but what specific evidence is out there in regards to IV patency and TKO?
2. It seems to me that if a patient has frequent IVPBs and the tubing is connected then disconnected frequently the chance for infection increases as compared to a patient with a TKO. Does anybody know about any evidence dealing with IV infection rates and TKO IVs.