My hospitals pharmacy has proposed the idea of mixing several antibiotics in syringes instead of IVPB bags of fluid as a cost saving measure. The proposed volumes are Ancef 1gm in 10ml, Maxipime 1gm in 25ml, and Rocephin 1 gm/25ml.
I don't have an issue with the Ancef, but I am concerned about the volumes of the Maxipime and Rocephin. (particularly if the patient doesn't have a running IV, as well as the 30 min infusion time).
I also have it in the back of my head that Rocephin is an irritant, but according to the pH and osmolality chart in the download section, all 3 drugs can be given through peripheral IV sites without risk of phlebitis. I checked the package inserts for Maxipime and Rocephin and both state that concentrations of 10mg/ml to 40mg/ml (voume of 10ml to 25ml) are recommended. No mention in either of need for further dilution.
Is anyone else seeing this in their facilities?
How do you deal with the patient who doesn't have a running IV, but just an intermittent lock?
Oncology CNS/Manager Outpatient Infusion Services