In the INS Core Curriculum for Infusion Nursing by Mary Alexander, there is information on page 95 regarding removing PICC's for infections. It states exceptions for catheter removal include the presence of Candida or other fungal infections. Does anyone know the rational behind this???? Recently we had a patient test positive for yeast from the blood drawn from the picc, but negative from blood drawn from the arm. The PICC tip was negative. The patient had yeast in his respiratory system, but not the same type. The patient also had yeast in the urine, but no culture was done for the type. Furthermore, the patient was on TPN and multiple antibiotics. I was upset that they blamed the infection on the PICC line and made us remove it. I have read this exception for removal before, but do not understand the rational so I can explain to the doctors that I do not have to remove a PICC for the presence of Candida???? Does anyone know the rational????