Lynn posted this message a while ago. I am looking for reference articles that substantiate the information other than the AmJnl of Nursing article form 8/07. It focused mostly on extravasation. I am looking for information on cool vs warm for infilration based onosmolarity, as stated:
Infiltration and Extravasation treatment
For minor infiltrations, no treatment may be required.
For major infiltrations, treatment depends on the osmolarity of the infiltrated drug. For hyperosmolar solutions, heat makes the situation worse. So cold is preferred.
For isotonic or hypotonic solutions, use heat or cold depending upon what makes the patient feel better.
For extravasation, again go by the tonicity of the solution, with 2 exceptions. Vince alkaloids and epipodophylotixins require heat and all others will usually receive cold.
Phlebitis is heat application. Lynn
Lynn Hadaway, M.Ed., RN, BC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Blog http://hadawayassociates.blogspot.com/
Office Phone 770-358-7861
You can find all of these resources in my online course on this topic. http://www.hadawayassociates.com/el_infil_extra.htm
I think there is ~90 references in that course. Sorry but I cannot provide reference lists as a free service. I was receiving so many requests, that I had to set some limits. Lynn
Lynn Hadaway, M.Ed., RN, NPD-BC, CRNI
Lynn Hadaway Associates, Inc.
PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861
Although oxaliplatin (chemptherapy) is not listed as a vesicant in the ONS Chemo/Bio 3rd edition, it can cause tissue injury resulting in very indurated and painful tissue (burning pain as it's primary toxicity is neuropathy). Heat is also recommended for oxaliplatin, based on suggestions in the literature. I hope to be publishing our experience with this.