Is anyone still using tPA alloquatted from pharmacy? Has anyone had to deal with a pharmacy who insists on sending 1mg doses instead of 2mg to declot central lines?
Our pharmacy has been doing this for years, and while I am trying to fight this, sent them the COOL 1 and COOL 2 studies, they now came up with a solution of diluting the 1mg dose of tPA into 2ml of sterile water. I am getting tired of talking to these pharmacists who are thinking this practice is alright because it will save money, when we all know if the clot is not completely removed, we are placing our patients at a higher risk for infection, etc. Help please!