Hello Everyone- I recently exchanged a picc over a wire that had been in for 6 days. The reason for this was that it cracked at the hub. It was 2 hours between the time it became cracked and the exchange procedure. This line was not a repairable line. Pt was afebrile and the site looked good. Our intensivist are saying they would not have changed the line and usually don't unless it is only like a day old. Remember they are referring to TLC because that is what they use. They feel the same way about a picc. Does anyone have any info or literature that supports when it is appropriate to change a line over a wire? I would appreciate it. Thanks!!