Is it considered best practice or the standard of care to have an impregnated disc applied to all central lines? It was my understanding they are very effective the first week post insertion, but there after there is not been substantial evidence of a difference. In home care we are currently using these on patients that have a high risk for infection, (immunesupressed, risk of non-compliance, poor environment, etc). Should these be placed on all patients? Is there any documentation of this?