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I am trying to find out info on infusing 2 differrent antibiotics a the same time using 2 separate i.v. sites.  I have always been told that you could only infuse one at a time.  Am I mistaken?  I did ask one of our pharmacist, he told me that yes you can infuse 2 at a time of course 2 different sites.  I would like to know where I could find this info?  thanks

There would be many factors

There would be many factors to consider. First would the risk of not being able to determine which drug caused a reaction if one should occur. With 2 different sites there should be no compatibility issues. Are these 2 ABX the only therapy being infused? If so, then why would you even need 2 sites? I have testified in a deposition that a dual lumen PICC was not needed when only 2 antibiotics were ordered because the larger diamter catheter increased the risk for vein thrombosis. So why waste veins by using 2 sites when this is all the therapy there is? Does not make sense to me. Lynn

Lynn Hadaway, M.Ed., RN, BC, CRNI

Lynn Hadaway Associates, Inc.

126 Main Street, PO Box 10

Milner, GA 30257


Office Phone 770-358-7861


Thankyou Lynn for responding, I should have given more info regarding this question.    I asked the question because this became an issue in the icu recently when a patient had multiple iv meds, including triple antibiotics. the patient at the time had 3 lines no central access and the nurse taking care of the patient was about to hang Bactrim, while zithromax was infusing ,this is when I told her that only one atbx could be infused at a time..eventually this pt. recieved a central line but this still would have been an issue.  Again I really dont know if they can be delivered at the same time, eventhough a pharmacist told me they could.  thankyou

Is there any nurse out there who is willing to share there protocol on extravasation of vesicant drugs, i.e. application of cold, steroid cream , manual injection of antidote.

Barbara Tinsley
We never run antibiotics at

We never run antibiotics at the same time  due to the problem of not knowing which abx is causing a reaction.  We have patients who would like to have two units of blood at the same time, we will not do that either, for the same reason.

Barbara Tinsley

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