Â Â Â Â This maybe a silly question, but I have to ask. Is it possible to have an air embolism in Power PICCÂ during insertion?? For example: If you have primed the PICC with saline and you do not put the caps on, and leave the clamps open ,can the end result be an air emblosim?? I have a bad habit of waiting to put my caps on after the picc is advanced, then I put caps on and apply the dressing. Thanks in advance for you input.